This was a multicentre, two-way, crossover study in 27 evaluable hypertensive patients with renal insufficiency following renal transplantation, who were maintained on a stable dose of CsA. Altman DG Practical statistics for medical research.
Generate a file for use with external citation management software. Hypertension after renal transplantation. N Engl J Med. Sustained improvement of renal graft function for two years in hypertensive renal transplant recipients treated with nifedipine as compared to lisinopril.
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This topic last updated: Other factors identified in the multivariate model as influencing rejection were human leucocyte antigen HLA matching at the DR locus, blood level of cyclosporin during the first week, HLA matching at the B locus, donor age and donor sex. Abstract Cyclosporine CsA impairs renal function, probably by preglomerular vasoconstriction.
Add to My Bibliography. Eur J Clin Invest Influence of nifedipine on interstitial fibrosis in renal transplant allografts treated with cyclosporin A.
Recommendations for the outpatient surveillance of renal transplant recipients. Citing articles via Web of Science View large Download slide GFR at 3 weeks control1 year and 2 years after transplantation.
National Center for Biotechnology InformationU. Calcineurin inhibitors and corticosteroids induce hypertension in most transplant recipients.
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Elevated blood pressure and pulse pressure can result in decreased allograft survival and left ventricular hypertrophy, with the latter being an independent risk factor for heart failure and death in the general population and renal transplant recipients [ ]. Abstract The effect of early nifedipine therapy on acute renal allograft rejection was studied in adult cadaveric transplant recipients.
Am J Kidney Dis. The effect of early nifedipine therapy on acute renal allograft rejection was studied in adult cadaveric transplant recipients. The combination of a decreased blood pressure with an increased RPF was reflected in a sharp decrease in renal vascular resistance 0. We have compared the effects of amlodipine mg once daily and nifedipine retard mg twice daily on renal function and blood pressure in renal transplant recipients treated with CsA. For more information on subscription options, click below on the option that best describes you:.
Left ventricular hypertrophy and combination therapy.